gene

MAP1S

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAP1S: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

13Outgoing

1Incoming

0Experiments

0Debates

Summary

Page for MAP1S - Microtubule Associated Protein 1S

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	MAP1S
Full Name	Microtubule Associated Protein 1S
Aliases	Page for MAP1S
Chromosome	19p13.3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	55 kDa
UniProt ID	Q9Y2R9
NCBI Gene ID	55130
Ensembl ID	ENSG00000131370
OMIM	607358
GeneCards	MAP1S
Human Protein Atlas	MAP1S
LC3 interaction domain	Direct binding to LC3 on autophagosomes
Microtubule-binding repeats	Multiple repeats that stabilize microtubules
Phosphorylation regulation	Activity modulated by phosphorylation
Associated Diseases	Als, Alzheimer, Ms
KG Connections	14 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MAP1S — AlphaFold Q9Y2R9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

MAP1S - Microtubule Associated Protein 1S

gene · 712 words

→

MAP1S Protein

protein · 586 words

→

Pathway Diagram

graph TD
    MAP1S["MAP1S"]
    Alzheimer{"Alzheimer"}
    MAP1S -->|"associated with"| Alzheimer
    Als{"Als"}
    MAP1S -->|"associated with"| Als
    Ms{"Ms"}
    MAP1S -->|"associated with"| Ms
    PSP["PSP"]
    MAP1S -->|"associated with"| PSP
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    MAP1S -->|"associated with"| ALZHEIMER_S_DISEASE
    ASTROCYTES["ASTROCYTES"]
    MAP1S -->|"associated with"| ASTROCYTES
    SP1["SP1"]
    MAP1S -->|"associated with"| SP1
    APOE["APOE"]
    MAP1S -->|"associated with"| APOE
    TAU["TAU"]
    MAP1S -->|"associated with"| TAU
    KIF13A["KIF13A"]
    MAP1S -->|"associated with"| KIF13A
    TRIM24["TRIM24"]
    MAP1S -->|"associated with"| TRIM24
    STX6["STX6"]
    MAP1S -->|"associated with"| STX6
    DUSP10["DUSP10"]
    DUSP10 -->|"associated with"| MAP1S
    style MAP1S fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (13)

Target	Relation	Type	Str
Alzheimer	associated_with	disease	0.65
Als	associated_with	disease	0.65
Ms	associated_with	disease	0.65
ALZHEIMER'S DISEASE	associated_with	gene	0.60
ASTROCYTES	associated_with	gene	0.60
PSP	associated_with	gene	0.60
SP1	associated_with	gene	0.60
APOE	associated_with	gene	0.60
TAU	associated_with	gene	0.60
KIF13A	associated_with	gene	0.60
TRIM24	associated_with	gene	0.60
STX6	associated_with	gene	0.60
MAPT	associated_with	gene	0.60

Incoming (1)

Source	Relation	Type	Str
DUSP10	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MAP1S in their description or question text

No additional research found