Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ITPKA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
ITPKA[ITPKA]
ITPKA -->|involved_in| Synaptic_plasticity[Synaptic plasticity]
ITPKA -->|implicated in| LRFN1[LRFN1]
ITPKA -->|implicated in| NCAN[NCAN]
ITPKA -->|implicated in| RAB3B[RAB3B]
ITPKA -->|implicated in| SLC1A2[SLC1A2]
ITPKA -->|implicated in| SYNPO[SYNPO]
ITPKA -->|implicated in| TUBB2B[TUBB2B]
ITPKA -->|activates| LPL[LPL]
ITPKA -->|activates| P2RX1[P2RX1]
ITPKA -->|activates| SPTLC2[SPTLC2]
CADM1[CADM1] -->|implicated in| ITPKA
COMT[COMT] -->|implicated in| ITPKA
ADRA2A[ADRA2A] -->|activates| ITPKA
ALDH1A2[ALDH1A2] -->|activates| ITPKA
IDH1[IDH1] -->|activates| ITPKA
FTLD[FTLD] -->|implicated in| ITPKA
IRS1[IRS1] -->|activates| ITPKA
benchmark_ot_ad_answer_key_ITP[benchmark_ot_ad_answer_key:ITPKA] -->|data_in| ITPKA| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ITPKA | data_in | dataset_row | 0.00 |
| Synaptic plasticity | involved_in | process | 0.80 |
| synaptic plasticity | participates_in | pathway | 0.60 |
| LPL | activates | gene | 0.60 |
| P2RX1 | activates | gene | 0.60 |
| SPTLC2 | activates | gene | 0.60 |
| SYNE2 | activates | gene | 0.60 |
| LRFN1 | implicated_in | gene | 0.60 |
| NCAN | implicated_in | gene | 0.60 |
| RAB3B | implicated_in | gene | 0.60 |
| SLC1A2 | implicated_in | gene | 0.60 |
| SYNPO | implicated_in | gene | 0.60 |
| TUBB2B | implicated_in | gene | 0.60 |
| RNA | implicated_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ITPKA in their description or question text
No additional research found