Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CYCLIN B1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CYCLIN B1 |
| Key Genes/Proteins | AKT, CDK1, ERK, PDK1, PI3K |
| Related Pathways | Cell Cycle, Differentiation, Mitosis, Pi3K/Akt, Pluripotency |
graph TD
CYCLIN_B1[CYCLIN B1]
CYCLIN_B1 -->|activates| CDK1[CDK1]
CYCLIN_B1 -->|regulates| PDK1[PDK1]
CYCLIN_B1 -->|regulates| AKT[AKT]
CYCLIN_B1 -->|regulates| Mitosis[Mitosis]
CYCLIN_B1 -->|regulates| Pluripotency[Pluripotency]
CYCLIN_B1 -->|regulates| Pi3K_Akt[Pi3K/Akt]
CYCLIN_B1 -->|regulates| Differentiation[Differentiation]
CYCLIN_B1 -->|activates| Stem_Cell[Stem Cell]
CYCLIN_B1 -->|regulates| Cell_Cycle[Cell Cycle]
CYCLIN_B1 -->|data_in| benchmark_ot_ad_answer_key_CYC[benchmark_ot_ad_answer_key:CYCLIN B1]
RB1[RB1] -->|regulates| CYCLIN_B1
PI3K[PI3K] -->|regulates| CYCLIN_B1
ERK[ERK] -->|regulates| CYCLIN_B1
benchmark_ot_ad_answer_key_CYC -->|data_in| CYCLIN_B1| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CYCLIN B1 | data_in | dataset_row | 0.00 |
| Pi3K/Akt | regulates | pathway | 0.60 |
| Differentiation | regulates | pathway | 0.60 |
| Stem Cell | activates | pathway | 0.60 |
| Cell Cycle | regulates | pathway | 0.60 |
| CDK1 | activates | gene | 0.60 |
| PDK1 | regulates | gene | 0.60 |
| AKT | regulates | gene | 0.60 |
| Mitosis | regulates | pathway | 0.60 |
| Pluripotency | regulates | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CYCLIN B1 | data_in | dataset_row | 0.00 |
| RB1 | regulates | gene | 0.70 |
| PI3K | regulates | gene | 0.60 |
| ERK | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CYCLIN B1 in their description or question text
No additional research found