concept

BAICALEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BAICALEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

55Connections

0Hypotheses

0Analyses

44Outgoing

11Incoming

0Experiments

0Debates

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💡 Concept Info

Name	BAICALEIN
Key Genes/Proteins	AMPK, BDNF, BECN1, CD274, CX3CR1, MTOR
Related Diseases	ALZHEIMER, ALZHEIMER'S DISEASE, APOPTOSIS, CANCER, CELL PROLIFERATION
Related Pathways	MTOR PATHWAY, MTOR SIGNALING

Pathway Diagram

graph TD
    BAICALEIN["BAICALEIN"]
    BAICALEIN -->|"inhibits"| MTOR["MTOR"]
    BAICALEIN -->|"targets"| CD274["CD274"]
    BAICALEIN -->|"inhibits"| Glutamine_mTOR_Metabolic_Pathw["Glutamine-mTOR Metabolic Pathway"]
    BAICALEIN -->|"promotes"| Apoptosis["Apoptosis"]
    BAICALEIN -->|"inhibits"| Glutamine_Mtor_Metabolic_Pathw["Glutamine-Mtor Metabolic Pathway"]
    BAICALEIN -->|"suppresses"| Tumor_Growth["Tumor Growth"]
    BAICALEIN -->|"suppresses"| Cell_Proliferation["Cell Proliferation"]
    Scutellaria_Baicalensis_Georgi["Scutellaria Baicalensis Georgi"] -->|"involved_in"| BAICALEIN

Outgoing (44)

Target	Relation	Type	Str
Tumor Growth	suppresses	phenotype	0.95
Glutamine-Mtor Metabolic Pathway	inhibits	pathway	0.95
Macroautophagic Degradation	associated_with	process	0.95
Cell Proliferation	suppresses	process	0.95
Glutamine-mTOR Metabolic Pathway	inhibits	pathway	0.95
MTOR	inhibits	protein	0.95
CD274	degrades	protein	0.95
Apoptosis	associated_with	process	0.95
CD274	targets	protein	0.95
Lung Cancer	treats	disease	0.90
mTOR	downregulates	protein	0.90
CD274-LC3 interaction	potentiates	process	0.90
CD274-LC3 Interaction	associated_with	process	0.90
Cd274-Lc3 Interaction	associated_with	mechanism	0.90
LAT1	inhibits	protein	0.90
ASCT2	inhibits	protein	0.90
GLS1	inhibits	protein	0.90
macroautophagy	induces	process	0.88
Tumor Development	inhibits	disease	0.85
LAT1	inhibits	protein	0.85
ASCT2	inhibits	protein	0.85
CD274	binds_to	protein	0.85
MTOR	inhibits	protein	0.80
Cancer	treats	disease	0.80
BDNF	activates	gene	0.70
AMPKα	binds	protein	0.70
CD274	activates	gene	0.65
MICROGLIA	activates	cell_type	0.65
ALZHEIMER'S DISEASE	treats	disease	0.65
TNF	inhibits	gene	0.65
LUNG CANCER	inhibits	disease	0.65
APOPTOSIS	activates	phenotype	0.65
MTOR SIGNALING	inhibits	pathway	0.65
CX3CR1	modulates	protein	0.60
BDNF	associated_with	gene	0.50
BECN1	associated_with	gene	0.50
AMPK	associated_with	gene	0.50
CD274	associated_with	gene	0.45
MICROGLIA	associated_with	cell_type	0.45
ALZHEIMER	associated_with	disease	0.45
TNF	associated_with	gene	0.45
CX3CR1	associated_with	gene	0.45
MTOR	associated_with	gene	0.45
CANCER	associated_with	disease	0.45

Incoming (11)

Source	Relation	Type	Str
Scutellaria Baicalensis Georgi	involved_in	compound	0.85
MAP1LC3B	enhances	gene	0.80
AMPK	inhibits	gene	0.70
APOPTOSIS	inhibits	phenotype	0.65
LUNG CANCER	associated_with	disease	0.45
CELL PROLIFERATION	associated_with	phenotype	0.45
TUMOR GROWTH	associated_with	phenotype	0.45
MTOR SIGNALING	associated_with	pathway	0.45
MTOR PATHWAY	associated_with	pathway	0.45
ALZHEIMER'S DISEASE	associated_with	disease	0.45
NEUROINFLAMMATION	associated_with	phenotype	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BAICALEIN in their description or question text

No additional research found