concept

116B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about 116B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

19Outgoing

0Incoming

0Experiments

0Debates

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💡 Concept Info

Name	116B
Key Genes/Proteins	CAT, GPX4, MAPK
Related Diseases	Ischemic Stroke

Pathway Diagram

graph TD
    n_116B[116B]
    n_116B -->|treats| Ischemic_Stroke[Ischemic Stroke]
    n_116B -->|downregulates| Infarct_Volume[Infarct Volume]
    n_116B -->|suppresses| microglia_activation[microglia activation]
    n_116B -->|suppresses| astrocyte_activation[astrocyte activation]
    n_116B -->|suppresses| inflammation[inflammation]
    n_116B -->|inhibits| Microglia[Microglia]
    n_116B -->|inhibits| Astrocytes[Astrocytes]
    n_116B -->|modulates| microtubule_dynamics[microtubule dynamics]

Outgoing (19)

Target	Relation	Type	Str
Ischemic Stroke	treats	disease	0.95
blood-brain barrier	associated_with	brain_region	0.92
Infarct Volume	downregulates	biomarker	0.92
Blood-Brain Barrier	associated_with	process	0.90
Mitochondrial Function	associated_with	process	0.90
Oxidative Stress	associated_with	process	0.90
inflammation	suppresses	process	0.90
microglia activation	inhibits	process	0.90
astrocyte activation	inhibits	process	0.90
ROS	associated_with	process	0.88
Astrocytes	inhibits	cell_type	0.88
Microglia	inhibits	cell_type	0.88
Gpx4	upregulates	enzyme	0.85
GPX4	upregulates	protein	0.85
CAT	upregulates	protein	0.85
microtubule dynamics	modulates	process	0.85
mitochondrial function	associated_with	process	0.85
MAPK	inhibits	protein	0.82
SOD1	upregulates	gene	0.78

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning 116B in their description or question text

No additional research found