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therapeutic 3,258 words KG: Urolithin A
Contents

Urolithin A for Neurodegeneration

💊 Therapeutic Info
NameUrolithin A
Key Genes/Proteinsamyloid beta, CTSZ, IL-6, IL6
Related DiseasesAlzheimer's disease, Alzheimer's Disease, Cognition
Related PathwaysLysosomal function

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Knowledge Graph

Related Hypotheses (30)

Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.92CYP46A1 Overexpression Gene Therapy
Score: 0.92SASP-Mediated Complement Cascade Amplification
Score: 0.91Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91Transcriptional Autophagy-Lysosome Coupling
Score: 0.88

Related Analyses (30)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · completed4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived

Related Experiments (30)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Selective Vulnerability of Dopaminergic Neurons — Mechanism
validation · proposed · Score: 0.40Proposed experiment from debate on TDP-43 undergoes liquid-l
falsification · proposed · Score: 0.40DLB Cognitive Fluctuation Mechanism Experiment
clinical · proposed · Score: 0.40DLB Treatment Response Biomarkers — Predicting Cholinesteras
clinical · proposed · Score: 0.40

See Also (15)

Beta-Propeller Protein-Associated Neurodegeneration (BP
disease · Pages share 139 hypothesesChina Neurodegeneration Epidemiology
disease · Pages share 139 hypothesesNeuroimaging for Parkinsonian Syndromes (NCT03872102)
clinical · Pages share 27 hypothesesSynaptic Biomarkers in Neurodegeneration
biomarker · Pages share 139 hypothesesOlfactory Mucosa, Blood and Urine for Identification of
clinical · Pages share 139 hypotheses

Knowledge Graph (12 edges)

Urolithin A inhibits RANKL
Urolithin A inhibits osteoclastogenesis
Urolithin A inhibits IL6
Urolithin A inhibits TNF
Urolithin A inhibits NF-kB pathway
Urolithin A inhibits NLRP3
Urolithin A inhibits Mitochondrial ROS Accumulation
Urolithin A modulates Calcium Homeostasis
Urolithin A regulates CTSZ
Urolithin A inhibits amyloid beta

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