| Gene Symbol | SRXN1 |
| Aliases | SRXN1PROTEIN |
| Chromosome | 20q13 |
| Function | SRXN1 (Sulfiredoxin 1) is a small antioxidant enzyme (125 amino acids) specialized in reducing overoxidized peroxiredoxins (Prxs). It catalyzes the ATP-dependent reduction of cysteine-sulfinic acid... |
| Amino Acids | 125 aa |
| Pathways | Oxidative Stress, Ferroptosis, Mtor, Oxidative Phosphorylation, Immune Response |
| GeneCards | SRXN1 |
| Human Protein Atlas | SRXN1 |
| Peroxiredoxins (PRDX1-6) | Primary substrates of SRXN1 |
| Thioredoxin system | Electron donor pathway for SRXN1 |
| Antioxidant response elements (ARE) | Transcriptional regulatory regions controlling SRXN1 expression |
| Associated Diseases | Inflammation, Lymphoma, Tumor |
| Interactions | CANCER, GENES, KEAP1, NRF2, OXIDATIVE STRESS, SLC7A11 |
| KG Connections | 69 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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