gene 1,534 words KG: RTN1
Contents

RTN1 Gene (Reticulon 1)

🧬 Gene Info
Gene SymbolRTN1
Full NameReticulon 1
AliasesReticulon-1
Chromosome19q13.32
Functionencodes a member of the reticulon family of proteins that are primarily localized to the endoplasmic reticulum (ER).
Primary Expressionneurons and is involved in shaping the tubular ER network, neuroendocrine secretory granule formation, and synaptic function
Subcellular Localizationthe endoplasmic reticulum (ER). Unlike its better-known relative RTN4 (Nogo), RTN1 is predominantly expressed in neurons
Amino Acids200 aa
Gene TypeProtein-coding
UniProt IDQ86VR8
NCBI Gene ID19740
Ensembl IDENSG00000131871
OMIM603123
GeneCardsRTN1
Human Protein AtlasRTN1
Associated DiseasesAlzheimer, Amyotrophic Lateral Sclerosis, disease, neurodegeneration, Neurodegenerative Diseases, Parkinson
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CHN1 associated_with RTN1
MDH1 associated_with RTN1
RTN1 associated_with SNAP25
AKT associated_with RTN1
RTN1 associated_with CHN1
RTN1 associated_with PI3K
SNAP25 associated_with RTN1
RTN1 associated_with MDH1
RTN1 associated_with neurodegeneration
MICRORNAS therapeutic_target RTN1

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