| Gene Symbol | UBQLN2 |
| Protein Family | Ubiquilin family |
| Function | Contains disease-causing mutations (P497H, P506T) |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | 66 kDa |
| Amino Acids | 600 aa |
| Exons | 11 |
| Pathways | Protein Degradation |
| UniProt ID | Q9R0R5 |
| GeneCards | UBQLN2 |
| Human Protein Atlas | UBQLN2 |
| Size | ~60 amino acids |
| Interaction | Facilitates delivery of ubiquitinated substrates to the proteasome |
| Structure | Proline-rich region with STI1-like heat shock chaperone motifs |
| Flexibility | Provides flexibility for substrate recognition |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, frontotemporal dementia, FTLD, Ms |
| Interactions | 26S Proteasome, AGING, ALS, AMYOTROPHIC LATERAL SCLEROSIS, APP, ATXN2 |
| KG Connections | 177 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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