| Gene Symbol | UBE2N |
| Full Name | Ubiquitin-Conjugating Enzyme E2 N |
| Aliases | UBE2NPROTEIN |
| Chromosome | 19q13.43 |
| Protein Type | Enzyme |
| Function | Initiation: UBE2N~Ub thioester forms via ATP-dependent charging |
| Subcellular Localization | </strong></td><td>Cytoplasm, Nucleus</td></tr> |
| Molecular Weight | 17 kDa |
| Pathways | NF-κB, NF-κB Signaling |
| UniProt ID | [P61079](https://www.uniprot.org/uniprot/P61079) |
| Ensembl ID | ENSG00000108987 |
| OMIM | 607252 |
| GeneCards | UBE2N |
| Human Protein Atlas | UBE2N |
| Core UBC Domain | Catalytic core (~150 aa) containing the active site |
| Associated Diseases | ALS |
| Interactions | Actin, CANCER, CDK1, CRBN, DNAJB6, FERROPTOSIS |
| KG Connections | 28 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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