| Gene Symbol | SESN1 |
| Aliases | SESN1PROTEIN |
| Chromosome | 6q21<br> |
| Function | SESN1 performs several critical cellular functions |
| Subcellular Localization | ** Cytoplasm, Nucleus<br> |
| Molecular Weight | 56 kDa |
| Pathways | mTOR, mtor, AMPK, AMPK signaling |
| UniProt ID | Q9Y7X8 |
| NCBI Gene ID | 27145 |
| Ensembl ID | ENSG00000080589 |
| GeneCards | SESN1 |
| Human Protein Atlas | SESN1 |
| N-terminal domain | Binds to GATOR2 complex for mTORC1 inhibition |
| C-terminal domain | Contains the active site for antioxidant enzyme activity |
| Walker A motif (P-loop) | Involved in ATP binding |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Metabolic Syndrome, Cancer |
| Interactions | CCND1, CDKN1A, DUSP1, NDRG2, PPP5C, PRKAA2 |
| KG Connections | 72 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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