protein 653 words KG: SCN8APROTEIN
Contents

SCN8A Protein (Sodium Voltage-Gated Channel Alpha Subunit 8)

🔬 Protein Info
Gene SymbolSCN8A
Full NameSodium Voltage-Gated Channel Alpha Subunit 8
AliasesSCN8A/Nav1.6 gene
Chromosome12q13.13
FunctionThe SCN8A gene encodes the alpha subunit of the voltage-gated sodium channel Nav1.6.
Primary ExpressionBrain, Cerebellum, Hippocampus, Cortex
Molecular Weight260 kDa
PathwaysAkt
UniProt IDQ9UQD0
NCBI Gene ID6334
Ensembl IDENSG00000175550
OMIM600402
GeneCardsSCN8A
Human Protein AtlasSCN8A
Associated DiseasesAtaxia, Inflammation, Ms, Parkinson
InteractionsCDK5R2, CREB, ERK, FGF13, GRM5, ISG15
KG Connections98 knowledge graph edges
DatabasesGeneCardsHPASTRING

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UniProtWikipedia

Related Hypotheses (7)

Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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