| Gene Symbol | NPTX2 |
| Full Name | Neuronal Pentraxin 2 |
| Aliases | NPTX2PROTEIN |
| Function | Neuronal Pentraxin 2 (NPTX2), also known as neuronal activity-regulated pentraxin (NARP), is a member of the pentraxin family of calcium-dependent ligand-binding proteins. |
| Subcellular Localization | </strong></td><td>Secreted, extracellular</td></tr> |
| Molecular Weight | 47 kDa |
| Pathways | COMPLEMENT, Complement |
| Ensembl ID | ENSG00000106290 |
| GeneCards | NPTX2 |
| Human Protein Atlas | NPTX2 |
| Synaptogenesis | Promotes excitatory synapse formation |
| Synaptic plasticity | Regulates AMPA receptor trafficking |
| Neuronal activity | Activity-dependent expression in excitatory neurons |
| Glutamate receptor clustering | Works with NPTXR to cluster AMPA receptors |
| Learning and memory | Critical for hippocampal synaptic plasticity |
| Associated Diseases | AD, ALI, ALS, Alzheimer, Alzheimer's disease |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID, AND, APOE |
| KG Connections | 200 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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