| Gene Symbol | NEFH |
| Full Name | Neurofilament Heavy Chain |
| Chromosome | 22q12.1 |
| Function | Neurofilament Heavy Chain (NF-H) is the largest neurofilament subunit (approximately 200 kDa) and plays critical roles in neuronal biology |
| Primary Expression | Large motor neurons, sensory neurons, brain (cortex, hippocampus, cerebellum) |
| Subcellular Localization | </th><td>Axons, neuronal cytoskeleton</td></tr> |
| Molecular Weight | 200 kDa |
| Amino Acids | 816 aa |
| Exons | 4 |
| UniProt ID | P06744 |
| NCBI Gene ID | 4744 |
| Ensembl ID | ENSG00000100133 |
| OMIM | 162400 |
| GeneCards | NEFH |
| Human Protein Atlas | NEFH |
| Associated Diseases | Aging, Als, Alzheimer, Inflammation, Ms, Neurodegeneration |
| Interactions | AGING, AKT1, CD9, CDK5, GSK3B, KIF5B |
| KG Connections | 94 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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