protein 894 words KG: LXRPROTEIN
Contents

LXR Protein (Liver X Receptor)

🔬 Protein Info
Gene SymbolLXR
AliasesLiver X Receptor
PathwaysNF-κB
GeneCardsLXR
Human Protein AtlasLXR
Associated DiseasesALS, Alzheimer, glioblastoma, neurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsABCA1, ABCA7, ABCG1, ACAT1, AKT, AMPK
SciDEX HypothesesUpstream restoration of glial lipid efflux and apo
KG Connections103 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (21)

TREM2-Dependent Microglial Senescence Transition
Score: 0.58
← Prevpg 2/2

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
nct05508789
clinical_trial · Pages share 4 hypotheses
MK-1167 Phase 2 AD Trial (MK-1167-008)
clinical · Pages share 4 hypotheses
A Placebo-Controlled, Double-Blind, Parallel-Group, 18-
clinical · Pages share 4 hypotheses
LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy
clinical · Pages share 4 hypotheses

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