| Gene Symbol | HMOX1 / HO-1 |
| Full Name | Heme Oxygenase 1 |
| Chromosome | 22q12 |
| Protein Type | Enzyme |
| Function | HMOX1 degrades heme to produce biliverdin (which is further converted to bilirubin), iron (which induces ferritin), and carbon monoxide (a signaling molecule). |
| Subcellular Localization | </strong></td><td>Microsomes, endoplasmic reticulum</td></tr> |
| Pathways | Autophagy, Chaperone, Immune Response, Mitophagy, Oxidative Stress |
| UniProt ID | P09601 |
| NCBI Gene ID | 3162 |
| Ensembl ID | ENSG00000101129 |
| OMIM | 141250 |
| Associated Diseases | Aging, Als, Alzheimer, Atherosclerosis, Diabetes |
| Known Drugs/Compounds | L. reuteri-CMVs, rapamycin |
| Interactions | ACHE, AKK, ALOX12, ALOX15, ALOX5, ALOXE3 |
| KG Connections | 500 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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