| Gene Symbol | HLA |
| Full Name | DRB1 Protein |
| Primary Expression | Ca1, Cortex |
| Subcellular Localization | </strong></td><td>Endosomal membrane, cell surface</td></tr> |
| Pathways | Jak-Stat, Apoptosis, Necroptosis, Epigenetic, Immune Response |
| GeneCards | HLA |
| Human Protein Atlas | HLA |
| Professional antigen-presenting cells | Dendritic cells, B cells, monocytes/macrophages |
| [Microglia](/entities/microglia) | Brain-resident immune cells, highly upregulated in neuroinflammation |
| Activated T cells | Low levels under inflammatory conditions |
| Non-hematopoietic cells | Some epithelial and endothelial cells under IFN-γ stimulation |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, Cardiovascular |
| Interactions | ABCA7, AGER, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOE |
| KG Connections | 291 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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