protein 1,709 words KG: HDAC9PROTEIN
Contents

HDAC9 Protein

🔬 Protein Info
Gene SymbolHDAC9
Full NameHistone Deacetylase 9
Chromosome7p21.1
Functionencodes a class IIa histone deacetylase that plays crucial roles in epigenetic regulation, transcriptional control, and cellular signaling in the brain.
Primary ExpressionBrain, heart, skeletal muscle
Molecular Weight110 kDa
UniProt IDQ9UKV0
NCBI Gene ID9734
Ensembl IDENSG00000048828
OMIM606365
GeneCardsHDAC9
Human Protein AtlasHDAC9
Associated DiseasesAls, Coronary Artery Disease, Inflammation, Stroke
InteractionsAND, HDAC, HDAC5, INFLAMMATION, KDR, METTL3
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

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UniProtWikipedia

Related Hypotheses (11)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (3)

Epigenetic Dysregulation in Huntington's Disease — Therapeut
validation · completed · Score: 0.40
Epigenetic Regulation Dysfunction in Alzheimer's and Parkins
clinical · proposed · Score: 0.40
Microglial Contributions to Huntington's Disease Pathogenesi
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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