protein 1,002 words KG: FXNPROTEIN
Contents

FXN Protein (Frataxin)

🔬 Protein Info
Gene SymbolFXN
AliasesFrataxin
Chromosome9q21.11
FunctionWithin this complex, frataxin
Primary ExpressionDorsal root ganglia, Spinal cord, Cerebellum, Heart, Pancreas, Liver
Subcellular Localization** Mitochondrial matrix (inner mitochondrial membrane)
Molecular Weight14 kDa
Amino Acids210 aa
PathwaysAutophagy, Mitophagy
UniProt IDQ16595
Ensembl IDENSG00000165060
OMIM606829
GeneCardsFXN
Human Protein AtlasFXN
N-terminal domainHydrophobic core, mediates dimerization
Associated DiseasesAtaxia, Friedreich's Ataxia, Migraine
InteractionsAND, C-MYC, HMOX1, MITOCHONDRIA, MYC, NAD
KG Connections61 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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