| Gene Symbol | EIF4G1 |
| Aliases | EIF4G1PROTEIN |
| Chromosome | 3p14.2 |
| Function | is a large scaffolding protein (approximately 175 kDa) that serves as the core component of the eIF4F translation initiation complex. |
| Molecular Weight | 220 kDa |
| Amino Acids | 1598 aa |
| Exons | 33 |
| Pathways | NF-κB, mTOR |
| Ensembl ID | ENSG00000114867 |
| GeneCards | EIF4G1 |
| Human Protein Atlas | EIF4G1 |
| TATA box | Located upstream of the transcription start site |
| GC-rich regions | Multiple Sp1 binding sites |
| Stress-responsive elements | CREB and ATF binding sites |
| Growth factor-responsive regions | STAT and NF-κB binding sites |
| Associated Diseases | neurodegeneration |
| Interactions | ATG5, ATP13A2, ATXN2, CASP1, CHMP3, DISC1 |
| KG Connections | 51 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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