| Gene Symbol | DNMT3A |
| Full Name | DNA Methyltransferase 3 Alpha |
| Aliases | DNA Methyltransferase 3A |
| Chromosome | 2p23 |
| Protein Type | Transferase |
| Function | DNMT3A encodes DNA methyltransferase 3 alpha, a de novo DNA methyltransferase that establishes new DNA methylation patterns during development and in adult tissues. |
| Primary Expression | neurons during development and in adulthood |
| Subcellular Localization | ** Nucleus |
| Molecular Weight | 130 kDa |
| Pathways | Dna Methylation, Epigenetic |
| UniProt ID | [Q9Y6K4](https://www.uniprot.org/uniprot/Q9Y6K4) |
| Ensembl ID | ENSG00000119772 |
| OMIM | 602950 |
| GeneCards | DNMT3A |
| Human Protein Atlas | DNMT3A |
| Associated Diseases | Als, Alzheimer, Cancer, Cardiovascular, Crohn'S Disease |
| Known Drugs/Compounds | GEMCITABINE |
| Interactions | AGING, ALZHEIMER, ALZHEIMER'S DISEASE, AND, ASXL1, BACE1 |
| SciDEX Hypotheses | DNMT3A-Mediated de novo Methylation Corrects 'Epig |
| KG Connections | 288 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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