| Gene Symbol | CLPP |
| Full Name | Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit |
| Aliases | Caseinolytic Mitochondrial Matrix Peptidase Proteolytic |
| Chromosome | 19p13.3 |
| Protein Type | Protease |
| Molecular Weight | 23.4 kDa |
| Amino Acids | 473 aa |
| Pathways | Mitochondrial Proteostasis |
| UniProt ID | [Q9NZJ5](https://www.uniprot.org/uniprot/Q9NZJ5) |
| Ensembl ID | ENSG00000139289 |
| GeneCards | CLPP |
| Human Protein Atlas | CLPP |
| N-terminal domain | Involved in substrate recognition and hexamer assembly |
| Catalytic serine protease domain | Contains the active site serine (Ser98) and catalytic triad |
| RecA-like ATPase domain | Present in the related CLPXP ATPase component (CLPX) |
| Associated Diseases | Aging, Als, Ataxia, frontotemporal dementia, Ftd, Ms |
| Interactions | Akt, AKT, CHCHD2, DNM1L, DRP1, FBXO7 |
| KG Connections | 238 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!