| Gene Symbol | CCNF |
| Aliases | Cyclin F |
| Function | Ccnf Protein (Cyclin F) plays an important role in the study of neurodegenerative diseases |
| Primary Expression | most tissues, with highest expression in: |
| Subcellular Localization | </th><td>Nucleus, Cytoplasm</td></tr> |
| Molecular Weight | 89.5 kDa |
| Amino Acids | 786 aa |
| Pathways | Apoptosis, Cell Cycle, apoptosis |
| GeneCards | CCNF |
| Human Protein Atlas | CCNF |
| F-box Domain (aa 1-47) | Mediates interaction with Skp1 and Cul1 to form the SCF ubiquitin ligase complex |
| Cyclin Box Domain (aa 51-165) | Binds to substrate proteins for ubiquitination |
| C-terminal Dimerization Region | Allows formation of functional dimers |
| Nuclear Localization Signal (NLS) | Facilitates nuclear import |
| SCF Complex Formation | Forms SCF^CCNF^ ubiquitin ligase complex with Skp1 and Cul1 |
| Associated Diseases | frontotemporal dementia |
| Interactions | ALS, APOPTOSIS, CDKN1A, CHCHD10, MATR3, NEK1 |
| KG Connections | 111 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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