| Gene Symbol | CASP3 |
| Full Name | Caspase 3 |
| Aliases | CASP3PROTEIN |
| Chromosome | 4q34 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 20 kDa |
| Amino Acids | 277 aa |
| Pathways | Akt, Apoptosis, Autophagy, Epigenetic, Glycolysis |
| UniProt ID | [P42574](https://www.uniprot.org/uniprot/P42574) |
| Ensembl ID | ENSG00000164305 |
| GeneCards | CASP3 |
| Human Protein Atlas | CASP3 |
| Prodomain | N-terminal domain (approximately 30-50 residues); short in executioner caspases |
| Large Subunit (p17) | ~17 kDa, contains the catalytic cysteine residue (C163) |
| Small Subunit (p12) | ~12 kDa, completes the active site |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer_disease, Alzheimer's disease |
| Known Drugs/Compounds | ANTHOCYANINS, aristolochic_acids, Atbc, berberine, BERBERINE, Bpmc |
| Interactions | ABP, ACHE, ACTB, AKT, AKT1, AKT1S1 |
| KG Connections | 1487 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!