protein 647 words KG: C1QCPROTEIN
Contents

C1QC Protein

🔬 Protein Info
Gene SymbolC1QC
AliasesC1QCPROTEIN
FunctionThe C1QC gene encodes the C chain of the C1q protein, which is the recognition component of the classical complement pathway.
Primary Expressionvarious tissues, with high expression in:
Molecular Weight26 kDa
Amino Acids245 aa
PathwaysComplement
Ensembl IDENSG00000166922
GeneCardsC1QC
Human Protein AtlasC1QC
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
InteractionsAIF1, APOC1, APOE, C1Q, C1QA, C1QB
KG Connections214 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (10)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
Complement C1q Mimetic Decoy Therapy
Score: 0.69
...
Score: 0.68
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Complement C1q Subtype Switching
Score: 0.66
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (9)

How does SPI1 transcriptionally regulate C1QA and C1QC expre
neuroinflammation · completed
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (13)

Gene expression validation in apoE-/- mice
validation · proposed · Score: 0.85
ox-LDL treatment of RAW264.7 macrophages
exploratory · proposed · Score: 0.85
Validation of hub genes in apoE-/- atherosclerotic mice
validation · proposed · Score: 0.80
Validation of hub genes in ox-LDL treated RAW264.7 macrophag
exploratory · proposed · Score: 0.80
Machine learning-based identification of C1Q hub genes
exploratory · proposed · Score: 0.90

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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