protein 587 words KG: BCL2L11PROTEIN
Contents

BCL2L11 Protein — BIM

🔬 Protein Info
Gene SymbolBCL2L11
Full NameBCL2 Like 11 (BIM)
Chromosome2q13
Functionis a potent pro-apoptotic BH3-only protein that belongs to the Bcl-2 family.
Primary ExpressionUbiquitous; high expression in neuronal tissues
Subcellular Localization</th><td>Cytosol (inactive); mitochondria (upon activation)</td></tr>
PathwaysMAPK signaling, Reactive Oxygen Species, apoptosis, apoptosis pathway, autophagy pathway
UniProt IDO43521
NCBI Gene ID10018
Ensembl IDENSG00000113194
OMIM603677
GeneCardsBCL2L11
Human Protein AtlasBCL2L11
Associated DiseasesAD, ALI, Als, Alzheimer, dementia
InteractionsABCD3, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1, AMPK
KG Connections462 knowledge graph edges
DatabasesGeneCardsHPASTRING

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