| Gene Symbol | BAK1 |
| Full Name | BCL2-Antagonist/Killer 1 |
| Aliases | BAK1PROTEIN |
| Chromosome | 6p21.31 |
| Protein Type | BCL2 family (pro-apoptotic) |
| Function | BAK1 is a 25 kDa protein localized primarily to the mitochondrial outer membrane |
| Subcellular Localization | </strong></td><td>Mitochondria (constitutively)</td></tr> |
| Molecular Weight | 25 kDa |
| Pathways | Ferroptosis, Mtor, Necroptosis, Pyroptosis, apoptosis |
| UniProt ID | Q9YM15 |
| NCBI Gene ID | 578 |
| Ensembl ID | ENSG00000130165 |
| GeneCards | BAK1 |
| Human Protein Atlas | BAK1 |
| BH3 Domain | Critical for interaction with anti-apoptotic proteins (BCL2, BCL-XL, MCL1) and for activation by BH3-only proteins |
| Associated Diseases | Als, oxidative stress, OXIDATIVE_STRESS, Tumor |
| Interactions | AMBRA1, ATP, BAX, BCL2, BECN1, BNIP3 |
| KG Connections | 148 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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