| Gene Symbol | APC |
| Aliases | APCPROTEIN |
| Chromosome | 5q22.2 |
| Protein Type | Gene |
| Function | is a tumor suppressor gene originally identified for its role in colorectal cancer, but increasingly recognized for its critical functions in the central nervous system. |
| Subcellular Localization | Cytoplasm, cell membrane, nucleus |
| Amino Acids | 843 aa |
| Pathways | Akt, Autophagy, Epigenetic, Mapk, Mtor |
| UniProt ID | P25054 |
| NCBI Gene ID | 324 |
| Ensembl ID | ENSG00000134982 |
| GeneCards | APC |
| Human Protein Atlas | APC |
| Oligomerization domain | Enables APC to form homodimers |
| Armadillo repeats | Mediate protein-protein interactions |
| Associated Diseases | Aging, Als, Cancer, Carcinoma, Colorectal Cancer, Tumor |
| Known Drugs/Compounds | rapamycin |
| Interactions | ADNP, AKT, AKT1, AKT1S1, AND, APOPTOSIS |
| KG Connections | 603 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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