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mechanism 3,033 words KG: NAD+
Contents

NAD+ Metabolism in Neurodegeneration

⚙ Mechanism Info
NameNAD+
Key Genes/ProteinsAMPK, CD38, CX43
Related DiseasesAlzheimer disease
Related Pathwayscellular senescence, epigenetic clocks
Linked Hypotheses22 hypotheses

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Knowledge Graph (12 edges)

NAD+ activates SIRT1
AMPK contributes_to NAD+
NAD+ regulates SIRT1
NAD+ modulates SIRT1
CD38 depletes NAD+
PARP degrades NAD+
SIRT degrades NAD+
NAD+ protects_against BLOOD-BRAIN BARRIER DAMAGE
NAD+ associated_with Cellular Processes
NAD+ modulates inflammation

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