Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYOFIBROBLAST: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYOFIBROBLAST |
graph TD
MYOFIBROBLAST[MYOFIBROBLAST]
MYOFIBROBLAST -->|contributes to| Kidney_Fibrosis[Kidney Fibrosis]
MYOFIBROBLAST -->|drives| kidney_fibrosis[kidney fibrosis]
MYOFIBROBLAST -->|mediates| Fibrosis[Fibrosis]
MYOFIBROBLAST -->|mediates| Extracellular_Matrix_Depositio[Extracellular Matrix Deposition]
Kidney_Fibrosis -->|causes| MYOFIBROBLAST
fibroblast[fibroblast] -->|involved_in| MYOFIBROBLAST
renal_fibroblast[renal fibroblast] -->|expressed in| MYOFIBROBLAST
pericyte[pericyte] -->|involved_in| MYOFIBROBLAST
epithelial_to_mesenchymal_tran[epithelial-to-mesenchymal transition] -->|contributes to| MYOFIBROBLAST| Target | Relation | Type | Str |
|---|---|---|---|
| kidney fibrosis | drives | disease | 0.95 |
| Kidney Fibrosis | contributes_to | disease | 0.95 |
| Kidney Fibrosis | involved_in | disease | 0.95 |
| Fibrosis | mediates | process | 0.90 |
| Extracellular Matrix Deposition | promotes | process | 0.85 |
| Extracellular Matrix Deposition | mediates | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Kidney Fibrosis | associated_with | disease | 0.95 |
| Kidney Fibrosis | causes | disease | 0.90 |
| Fibroblast | associated_with | cell_type | 0.85 |
| fibroblast | involved_in | cell_type | 0.85 |
| renal fibroblast | expressed_in | cell_type | 0.85 |
| pericyte | involved_in | cell_type | 0.75 |
| Epithelial Cell | associated_with | cell_type | 0.75 |
| Endothelial Cell | associated_with | cell_type | 0.75 |
| epithelial-to-mesenchymal transition | contributes_to | process | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MYOFIBROBLAST in their description or question text
No additional research found