Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KRTAPS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | KRTAPS |
| Key Genes/Proteins | GENES, INFLAMMATION, MMP7, RNA |
| Related Diseases | Als, ALS, Fibrosis, Inflammation |
graph TD
KRTAPS["KRTAPS"]
KRTAPS -->|"involved_in"| Keratinization["Keratinization"]
KRTAPS -->|"target for"| Als["Als"]
KRTAPS -->|"expressed in"| ALS["ALS"]
KRTAPS -->|"expressed in"| Inflammation["Inflammation"]
KRTAPS -->|"target for"| RNA["RNA"]
KRTAPS -->|"inhibits"| Epithelial["Epithelial"]
KRTAPS -->|"inhibits"| T_Cell["T Cell"]
Metformin["Metformin"] -->|"upregulates"| KRTAPS
INFLAMMATION["INFLAMMATION"] -->|"expressed in"| KRTAPS
RNA -->|"target for"| KRTAPS| Target | Relation | Type | Str |
|---|---|---|---|
| Keratinization | involved_in | process | 0.75 |
| Fibrosis | associated_with | disease | 0.65 |
| Als | therapeutic_target | disease | 0.65 |
| ALS | expressed_in | disease | 0.65 |
| Inflammation | expressed_in | disease | 0.65 |
| RNA | expressed_in | gene | 0.60 |
| MMP7 | associated_with | gene | 0.60 |
| RNA | therapeutic_target | gene | 0.60 |
| Epithelial | inhibits | cell_type | 0.60 |
| T Cell | inhibits | cell_type | 0.60 |
| INFLAMMATION | expressed_in | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Metformin | upregulates | drug | 0.88 |
| RNA | therapeutic_target | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| INFLAMMATION | expressed_in | gene | 0.60 |
| MMP7 | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KRTAPS in their description or question text
No additional research found