gene 946 words KG: XRCC3
Contents

XRCC3

🧬 Gene Info
Gene SymbolXRCC3
Full NameX-Ray Repair Cross Complementing 3
Chromosome14q32.33
FunctionXRCC3 functions primarily in the homologous recombination pathway of DNA double-strand break (DSB) repair:
Subcellular Localization## Protein Structure
Molecular Weight38 kDa
PathwaysApoptosis, Invasion
UniProt ID[Q9UQE5](https://www.uniprot.org/uniprot/Q9UQE5)
Ensembl IDENSG00000113147
OMIM600675
GeneCardsXRCC3
Human Protein AtlasXRCC3
Associated DiseasesTumor
InteractionsAPOPTOSIS, BAX, CANCER, DNA, P53
KG Connections16 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

SASP-Mediated Complement Cascade Amplification
Score: 0.70

Related Analyses (2)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (8)

Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: activates
Tumor Necrosis Factor (TNF)
entity · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: activates
Genes
index · KG edge: expressed_in

Knowledge Graph (12 edges)

XRCC3 activates BAX
BAX activates XRCC3
XRCC3 expressed_in GENES
XRCC3 activates DNA
XRCC3 activates P53
XRCC3 activates Cancer
XRCC3 activates Als
XRCC3 associated_with Tumor
XRCC3 activates Apoptosis
APOPTOSIS activates XRCC3

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.