gene 711 words KG: UBE2K
Contents

UBE2K Gene

🧬 Gene Info
Gene SymbolUBE2K
Full NameUbiquitin Conjugating Enzyme E2 K
Chromosome1p34.3
Protein TypeEnzyme
Molecular Weight22 kDa
Amino Acids150 aa
PathwaysNF-κB
UniProt IDP61006
Ensembl IDENSG00000109381
GeneCardsUBE2K
Human Protein AtlasUBE2K
UbiquitinationCatalyzes ubiquitin chain formation
K63-linked chainsGenerates K63-linked polyubiquitin
DNA repairInvolved in DNA damage response
[NF-κB](/entities/nf-kb) signalingRegulates inflammatory responses
Associated Diseasesneurodegeneration
KG Connections18 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.95
PARP1 Inhibition Therapy
Score: 0.74
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61

Related Analyses (4)

Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Neurodegeneration
disease · KG edge: implicated_in
necroptosis
general · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulates
ARID1A
gene · KG edge: associated_with
BMAL1 (ARNTL) Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

ARID1A associated_with UBE2K
CANX associated_with UBE2K
UBE2K associated_with RPL14
UBE2K associated_with EEF2
UBE2K expressed_in CREB1
UBE2K associated_with Rb
autophagy regulates UBE2K
BMAL1 regulates UBE2K
CLOCK regulates UBE2K
UBE2K participates_in circadian regulation

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