gene 618 words KG: TRPC3
Contents

TRPC3 Gene

🧬 Gene Info
Gene SymbolTRPC3
Full NameTransient Receptor Potential Cation Channel Subfamily C Member 3
Chromosome4q27
Protein TypeReceptor
FunctionTRPC3 is a non-selective cation channel involved in synaptic plasticity and motor coordination.
Primary Expressionthe nervous system and participate in sensory perception, neuroprotection, and disease processes
UniProt ID[Q9UQC2](https://www.uniprot.org/uniprotkb/Q9UQC2/entry)
GeneCardsTRPC3
Human Protein AtlasTRPC3
Associated DiseasesAtaxia, synaptic plasticity
InteractionsApp, Bdnf, BDNF, CAV1, CAV3, MIRO1
KG Connections19 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

SASP-Mediated Complement Cascade Amplification
Score: 0.98
CYP46A1 Overexpression Gene Therapy
Score: 0.98
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (11)

NeuRon Therapeutics
company · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Mitochondria
entity · KG edge: activates
BDNF Gene
gene · KG edge: activates
CAV1
gene · KG edge: activates

Knowledge Graph (12 edges)

BDNF activates TRPC3
TRPC6 activates TRPC3
TRPC3 activates PI3K
TRPC3 activates MIRO1
TRPC3 activates TRKB
TRPC3 activates BDNF
TRPC3 activates TRPC6
MIRO1 activates TRPC3
PI3K activates TRPC3
TRPC3 activates CAV1

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