gene 1,466 words KG: TMBIM6
Contents

TMBIM6 Gene

🧬 Gene Info
Gene SymbolTMBIM6
Full NameTransmembrane BAX Inhibitor Motif Containing 6 (BAX Inhibitor 1)
AliasesBAX Inhibitor 1/BI1
Chromosome12q13.12
Functionis a highly conserved anti-apoptotic protein localized primarily to the endoplasmic reticulum (ER) membrane.
Molecular Weight33 kDa
Amino Acids299 aa
PathwaysPyroptosis
Ensembl IDENSG00000125148
GeneCardsTMBIM6
Human Protein AtlasTMBIM6
Associated Diseasesneurodegeneration
InteractionsBAX, GENES, PIEZO1, PYROPTOSIS
KG Connections7 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (13)

Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Extracellular Matrix Stiffness Modulation
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (6)

Cardiac MIBG Scan for Parkinsonism
diagnostic · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: activates
BAX Gene
gene · KG edge: activates
PIEZO1 — Piezo Type Mechanosensitive Ion Channel Compon
gene · KG edge: activates

Knowledge Graph (7 edges)

BAX activates TMBIM6
PIEZO1 activates TMBIM6
PYROPTOSIS activates TMBIM6
GENES activates TMBIM6
TMBIM6 therapeutic_target Cancer
TMBIM6 activates Cardiac
TMBIM6 activates Pyroptosis

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