gene 1,883 words KG: STATHMIN
Contents

STATHMIN — Stathmin-1 (Oncoprotein 18)

🧬 Gene Info
Gene SymbolSTATHMIN
Full NameStathmin-1 (Oncoprotein 18)
Chromosome8q11.23
Functionis a microtubule-destabilizing phosphoprotein that plays a critical role in regulating microtubule dynamics, neuronal development, and synaptic plasticity.
Primary ExpressionBrain (cortex, hippocampus), Testis, Lymphocytes
Molecular Weight18 kDa
Amino Acids149 aa
Exons6
PathwaysAxonal Transport, Tdp-43
UniProt IDP16949
NCBI Gene ID3925
Ensembl IDENSG00000117682
OMIM151440
GeneCardsSTATHMIN
Human Protein AtlasSTATHMIN
Associated DiseasesAls, Tumor
InteractionsALS, AMYOTROPHIC LATERAL SCLEROSIS, DEMENTIA, DNA, NEFL, NEURODEGENERATION
KG Connections82 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (4)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Cryptic Exon Silencing Restoration
Score: 0.53
Quantum Coherence Disruption in Cellular Communication
Score: 0.63

Related Analyses (4)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

See Also (9)

Amyotrophic Lateral Sclerosis
redirect · KG edge: inhibits
Frontotemporal Dementia (FTD)
disease · KG edge: activates
Neurodegeneration
disease · KG edge: regulates
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: activates
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: inhibits

Knowledge Graph (12 edges)

C9ORF72 expressed_in STATHMIN
ABCB1 associated_with STATHMIN
STATHMIN-2 inhibits STATHMIN
STATHMIN expressed_in C9ORF72
STATHMIN associated_with ABCB1
STATHMIN regulates STATHMIN-2
STATHMIN interacts_with STATHMIN-2
C9ORF72 activates STATHMIN
STATHMIN activates STATHMIN-2
STATHMIN inhibits STATHMIN-2

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