| Gene Symbol | MTCL1 |
| Full Name | Microtubule Cross-Linking Factor 1 |
| Chromosome | 21q22.3 |
| Protein Type | Gene |
| Function | is a human gene encoding a microtubule-associated protein (MAP) that promotes microtubule bundling and stabilization in cells[@shorabe2005]. |
| Primary Expression | the brain, where it plays critical roles in neuronal polarity, axonal transport, and dendritic spine morphogenesis |
| Molecular Weight | 230 kDa |
| Amino Acids | 104 aa |
| Exons | 35 |
| Pathways | COMPLEMENT, Complement, Epigenetic, Wnt |
| GeneCards | MTCL1 |
| Human Protein Atlas | MTCL1 |
| Coiled-coil motifs | Enable protein dimerization and bundling |
| EB-binding sites | Interact with end-binding proteins |
| Phosphorylation sites | Multiple serine/threonine sites for regulation |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | AND, App, BETA-CATENIN, C1Q, C1QBP, COMPLEMENT |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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