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gene 624 words KG: LRP10
Contents

LRP10

🧬 Gene Info
Gene SymbolLRP10
Protein TypeReceptor
FunctionLRP10 is a transmembrane receptor protein involved in
Primary Expressionneurons and has been implicated in endosomal-lysosomal trafficking and protein clearance pathways
GeneCardsLRP10
Human Protein AtlasLRP10
Associated DiseasesParkinson's disease
InteractionsALZHEIMER'S DISEASE, APP, ENDOSOMES, SORL1
KG Connections31 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (19)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71LRP1-Dependent Tau Uptake Disruption
Score: 0.58TREM2-Dependent Microglial Senescence Transition
Score: 0.95

Related Analyses (5)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

Anti-Tau Immunotherapy Dosing Optimization
clinical · proposed · Score: 0.40Tau PET Pattern as Therapeutic Response Predictor in 4R-Tauo
clinical · proposed · Score: 0.40Tau Propagation Causality Test — Does Tau Spread Drive Neuro
clinical · proposed · Score: 0.40

See Also (15)

APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: activatesMicroglia
cell · KG edge: expressed_inAPOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_withAlzheimer Indonesia
institution · KG edge: expressed_inLDLR Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

APOE associated_with LRP10
LRP10 associated_with LDLR
LRP10 activates APP
LRP10 associated_with TREM2
LRP10 expressed_in TREM2
LRP10 expressed_in APOE
APOE expressed_in LRP10
LRP10 expressed_in Rb
LRP10 activates neurodegeneration
LRP10 interacts_with SORL1

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