gene 3,191 words KG: LMX1B
Contents

LMX1B Gene

🧬 Gene Info
Gene SymbolLMX1B
Chromosome9q33.3
Protein TypeTranscription Factor
Functionencodes a critical transcription factor required for the proper development and maintenance of dopaminergic neurons in the midbrain.
Molecular Weight41 kDa
Amino Acids372 aa
Exons5
PathwaysAlpha-Synuclein, Er Stress, Synaptic Plasticity
UniProt IDO43823
NCBI Gene ID4010
Ensembl IDENSG00000136944
OMIM602575
GeneCardsLMX1B
Human Protein AtlasLMX1B
Associated DiseasesParkinson
KG Connections35 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (9)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Correcting Gut Microbial Dopamine Imbalance to Support Syste
Score: 0.61
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73

Related Analyses (8)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

See Also (11)

Neurofilament Medium Chain (NfM) - Biomarker
biomarker · KG edge: regulates
Parkinson Basal Ganglia Circuit
circuit · KG edge: regulates
PINK1 (PTEN-Induced Kinase 1)
entity · KG edge: regulates
HNRNPA1 Gene
gene · KG edge: regulates
NURR1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

HNRNPA1 regulates LMX1B
PARK7 regulates LMX1B
PINK1 regulates LMX1B
NFM regulates LMX1B
LMX1B associated_with NURR1
LMX1B regulates SNCA
LMX1B regulates PINK1
LMX1B regulates SFPQ
LMX1B regulates NFM
LMX1B regulates HNRNPA1

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