| Gene Symbol | KCNJ2 |
| Full Name | Kir2.1 Inward Rectifier Potassium Channel |
| Chromosome | 17q24.3 |
| Protein Family | Inward rectifier potassium channel (Kir) family |
| Protein Type | Channel |
| Function | encodes a 493-amino acid protein. |
| Amino Acids | 493 aa |
| Pathways | Neurovascular Coupling |
| UniProt ID | P48745 |
| NCBI Gene ID | 3760 |
| OMIM | 600681 |
| GeneCards | KCNJ2 |
| Human Protein Atlas | KCNJ2 |
| Transmembrane domains | Two transmembrane helices (M1 and M2) that form the channel pore |
| P-loop | Pore helix and selectivity filter between M1 and M2 with the highly conserved GYG sequence |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, BRAIN INJURY, C9ORF72, DEMENTIA |
| KG Connections | 19 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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