gene 2,123 words KG: HNRNPM
Contents

HNRNPM Gene

🧬 Gene Info
Gene SymbolHNRNPM
Chromosome19p13.3
FunctionRNA Recognition Motifs (RRMs): Four RRMs (RRM1-4) in the central region enable sequence-specific RNA binding.
Primary Expressionall tissues examined - Highest expression in brain, heart, and skeletal muscle - In the brain, localized to neurons throughout cortex, hippocampus, an
Subcellular Localizationneurons throughout cortex, hippocampus, and cerebellum
Molecular Weight77 kDa
Amino Acids730 aa
Ensembl IDENSG00000177868
GeneCardsHNRNPM
Human Protein AtlasHNRNPM
Associated Diseasesneurodegeneration
InteractionsCANCER, RBFOX2
KG Connections6 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (11)

Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Cross-Seeding Prevention Strategy
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Arginine Methylation Enhancement Therapy
Score: 0.65

Related Analyses (7)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

Familial vs Sporadic Neurodegeneration Comparison
disease · Pages share 7 hypotheses
mitochondrial-dysfunction-neurodegeneration-comparison
disease · Pages share 7 hypotheses
DALY Methodology — Neurodegeneration
disease · Pages share 6 hypotheses
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 6 hypotheses
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 6 hypotheses

Knowledge Graph (6 edges)

RBFOX2 interacts_with HNRNPM
RAC1 expressed_in HNRNPM
MYC regulates HNRNPM
CANCER interacts_with HNRNPM
HNRNPM interacts_with Cancer
HNRNPM regulates Tumor

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