| Gene Symbol | GNB5 |
| Chromosome | 15q21.1 |
| Protein Type | Gene |
| Function | encodes a brain-specific G protein beta subunit that plays critical roles in neuronal GPCR signaling. |
| Molecular Weight | 37.5 kDa |
| Amino Acids | 395 aa |
| Exons | 12 |
| GeneCards | GNB5 |
| Human Protein Atlas | GNB5 |
| Huntington's Disease | Altered G protein signaling has been reported in Huntington's disease (HD) models, and GNB5 may contribute to medium spiny neuron dysfunction [12] |
| Amyotrophic Lateral Sclerosis (ALS) | G protein-coupled pathways are involved in motor neuron survival, and GNB5 variants may modify disease progression [13] |
| Associated Diseases | oxidative stress |
| Interactions | RGS |
| KG Connections | 37 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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