| Gene Symbol | FRDA |
| Function | encodes a small mitochondrial protein that plays a critical role in iron-sulfur cluster (Fe-S) biogenesis, mitochondrial energy production, and cellular iron homeostasis. |
| Molecular Weight | ~14 kDa (precursor), ~8 kDa (mature) |
| Amino Acids | 210 aa |
| Ensembl ID | ENSG00000165060 |
| GeneCards | FRDA |
| Human Protein Atlas | FRDA |
| Precursor | ~210 amino acids |
| Mature form | ~130 amino acids after processing |
| Molecular weight | ~14 kDa (precursor), ~8 kDa (mature) |
| N-terminal helix | Mitochondrial targeting sequence (cleaved) |
| α-helical domain | Forms the core structure |
| β-sheet domain | Contains the iron-binding surface |
| Iron-binding sites | Acidic residues on the protein surface |
| Ferroxidase activity | Can oxidize Fe²⁺ to Fe³⁺ |
| Associated Diseases | ALS, Ataxia, neurodegeneration |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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