| Gene Symbol | FGF8 |
| Full Name | Fibroblast Growth Factor 8 |
| Chromosome | 10q24.33 |
| Function | encodes a critical signaling molecule belonging to the FGF family of heparin-binding growth factors. |
| Primary Expression | Brain (frontal cortex, hippocampus), substantia nigra, hypothalamus, SVZ |
| Molecular Weight | 24 kDa |
| Amino Acids | 215 aa |
| Pathways | Akt, Mapk, Pi3K, Pi3K/Akt |
| UniProt ID | [P55075](https://www.uniprot.org/uniprot/P55075) |
| Ensembl ID | ENSG00000107882 |
| GeneCards | FGF8 |
| Human Protein Atlas | FGF8 |
| FGF8a | The most common isoform, widely expressed during development |
| FGF8b | More potent in certain contexts, particularly in neural specification |
| FGF8c/d/e/f | Less characterized isoforms with tissue-specific expression |
| Associated Diseases | neurodegeneration |
| KG Connections | 52 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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