| Gene Symbol | FAM171A2 |
| Full Name | Neuronal Receptor for Alpha-Synuclein |
| Chromosome | 10q21.3 |
| Function | is a gene encoding a neuronal transmembrane protein that functions as a receptor for alpha-synuclein fibrils. |
| Subcellular Localization | positions FAM171A2 to intercept extracellular |
| Amino Acids | 614 aa |
| Exons | 12 |
| Pathways | Oxidative Stress |
| UniProt ID | [Q6ZMP3](https://www.uniprot.org/uniprot/Q6ZMP3) |
| Ensembl ID | ENSG00000171970 |
| GeneCards | FAM171A2 |
| Human Protein Atlas | FAM171A2 |
| Substantia nigra | Highest expression in dopaminergic neurons of the substantia nigra pars compacta — the exact neuronal population that degenerates in Parkinson's disease |
| Cerebral cortex | Moderate expression in cortical neurons, particularly layer 5 pyramidal neurons |
| Hippocampus | Expression in CA1 and CA3 pyramidal neurons and dentate gyrus granule cells |
| Associated Diseases | Parkinson |
| Interactions | CAT, GPX1, GRN, SOD1, TNF |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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