gene 2,701 words KG: CSNK1D
Contents

CSNK1D - Casein Kinase 1 Delta

🧬 Gene Info
Gene SymbolCSNK1D
Full NameCasein Kinase 1 Delta
Chromosome15q21.3
Protein TypeKinase
Functionis a serine/threonine protein kinase that plays critical roles in multiple cellular processes, including circadian rhythm regulation, Wnt signaling, DNA damage response, and protein trafficking.
Primary ExpressionBrain (hypothalamus, SCN, cortex, hippocampus), liver, lung
Molecular Weight47 kDa
Amino Acids409 aa
PathwaysWnt signaling, wnt
UniProt IDP48730
NCBI Gene ID1453
Ensembl IDENSG00000141552
OMIM604065
GeneCardsCSNK1D
Human Protein AtlasCSNK1D
Associated DiseasesAlzheimer's disease, Parkinson's disease, Huntington's disease
InteractionsALS, AMYOTROPHIC LATERAL SCLEROSIS, CSNK1E, GAPVD1, MOTOR NEURONS, PER1
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (10)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.71

Related Analyses (3)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Amyotrophic Lateral Sclerosis
redirect · KG edge: inhibits
Neurodegeneration
disease · KG edge: implicated_in
CSNK1E - Casein Kinase 1 Epsilon
gene · KG edge: inhibits
PTCH1 — Patched 1 (Hedgehog Receptor)
gene · KG edge: regulates
SHH — Sonic Hedgehog
gene · KG edge: regulates

Knowledge Graph (12 edges)

CSNK1D inhibits CSNK1E
CSNK1D activates Wnt/β-catenin pathway
CSNK1D activates Hedgehog-GLI pathway
CSNK1D regulates SHH
CSNK1D regulates PTCH1
CSNK1D regulates Oxidative phosphorylation
CSNK1D phosphorylates TDP-43
CSNK1D phosphorylates GAPVD1
CSNK1D participates_in Ciliogenesis
CSNK1D regulates Cell proliferation

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