gene 4,497 words KG: CNTN4
Contents

CNTN4 — Contactin 4

🧬 Gene Info
Gene SymbolCNTN4
Full NameContactin 4
Chromosome3
Protein FamilyImmunoglobulin superfamily; Contactin family
Protein TypeGPI-anchored neural cell adhesion molecule
Functionis a GPI-anchored protein that localizes to lipid rafts in neuronal membranes where it mediates cell surface interactions essential for neural circuit formation and maintenance [@pmid_15342350].
Primary ExpressionBrain (cortex, hippocampus, cerebellum), peripheral tissues
Molecular Weight~116 kDa
Amino Acids028 aa
Exons24
UniProt IDQ9C0A2
NCBI Gene ID55299
Ensembl IDENSG00000144619
GeneCardsCNTN4
Human Protein AtlasCNTN4
Associated DiseasesALS, Amyotrophic Lateral Sclerosis
KG Connections77 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (1)

Netrin-1 Gradient Restoration
Score: 0.59

Related Analyses (2)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived

Related Experiments (6)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
CRISPR Gene Correction Approaches for CBS/PSP
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (9)

Cerebellum
brain · KG edge: expressed_in
Amyotrophic Lateral Sclerosis
redirect · KG edge: expressed_in
Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
ATXN2 Gene
gene · KG edge: encodes
BID — BH3 Interacting Domain Death Agonist
gene · KG edge: encodes

Knowledge Graph (12 edges)

ATXN2 expressed_in CNTN4
HNRNPA1 expressed_in CNTN4
CNTN4 expressed_in PLIN4
CNTN4 expressed_in BID
CNTN4 expressed_in HNRNPA2B1
CNTN4 expressed_in TDP-43
CNTN4 expressed_in TBC1D24
CNTN4 expressed_in MAPT
CNTN4 expressed_in CDKN1A
CNTN4 expressed_in TIA1

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