| Gene Symbol | CALCA |
| Function | It acts as a neuropeptide transmitter in primary sensory neurons (Aδ and C fibers) and modulates pain signals at both peripheral and central terminals. |
| Amino Acids | 32 aa |
| Exons | 6 |
| Ensembl ID | ENSG00000110680 |
| GeneCards | CALCA |
| Human Protein Atlas | CALCA |
| Calcitonin | A 32-amino acid peptide hormone primarily involved in calcium homeostasis, secreted by thyroid C-cells |
| α-CGRP | The predominant neuropeptide form in the nervous system |
| Katacalcin | A shorter peptide with uncertain function |
| CLR/RAMP1 receptor | The canonical CGRP receptor |
| CLR/RAMP2 or RAMP3 receptors | Associated with AM (adrenomedullin) receptors |
| Associated Diseases | neurodegeneration |
| Interactions | Bdnf, BDNF, CRH, CRHR1, FKBP5, IL18 |
| KG Connections | 33 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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