gene 1,736 words KG: C4A
Contents

C4A Gene

🧬 Gene Info
Gene SymbolC4A
Full NameComplement Component 4A (Chido/Rodgers Blood Group)
AliasesComplement component C4A gene, Complement Component 4A
Chromosome6p21.3
Functionencodes a critical protein in the classical complement cascade, a key component of the innate immune system.
Molecular Weight104 kDa
Amino Acids1741 aa
UniProt IDP0C0P0
NCBI Gene ID712
Ensembl IDENSG00000144711
OMIM120810
GeneCardsC4A
Human Protein AtlasC4A
Associated DiseasesAls
InteractionsC4, C4B, PSP
KG Connections36 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (15)

TREM2-Dependent Microglial Senescence Transition
Score: 0.95
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
APOE-TREM2 Interaction Modulation
Score: 0.74

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

NeuRon Therapeutics
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: expressed_in
Genes
index · KG edge: expressed_in
C4B Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

C4A expressed_in C4B
C4B expressed_in C4A
C4 interacts_with C4A
C4A interacts_with C4B
C4A interacts_with schizophrenia
C4A regulates MAPT
C4A regulates PSP
C4A regulates STX6
C4A interacts_with PSP
C4A causes PSP

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