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gene 1,033 words KG: ARID1B
Contents

ARID1B

🧬 Gene Info
Gene SymbolARID1B
Chromosome6q25.3
FunctionBAF chromatin remodeling complex subunit
Amino Acids2236 aa
Exons20
PathwaysEpigenetic, Wnt, epigenetic regulation
Ensembl IDENSG00000049618
GeneCardsARID1B
Human Protein AtlasARID1B
Associated DiseasesAls, Autism, autism spectrum disorder
KG Connections18 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76APOE-TREM2 Interaction Modulation
Score: 0.74Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58TREM2-Dependent Microglial Senescence Transition
Score: 0.58Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (22)

Experiment Validation: In vitro ThT Assay
validation · proposed · Score: 0.40Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (6)

GABA (Gamma-Aminobutyric Acid) - Neurodegenerative Dise
biomarker · KG edge: regulatesNeurodegeneration
disease · KG edge: implicated_inEpigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: regulatesPVALB Gene - Parvalbumin
gene · KG edge: regulatesPackard Center for ALS Research
institution · KG edge: causes

Knowledge Graph (12 edges)

PVALB regulates ARID1B
ARID1B regulates PVALB
ARID1B regulates Neural Progenitor
ARID1B causes Rb
ARID1B regulates GABA
ARID1B causes Als
ARID1B causes Autism
ARID1B regulates Epigenetic
ARID1B regulates Wnt
ARID1B regulates WNT

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